Ophthalmics
At Dompé, our R&D strives to address areas of unmet clinical need. This is what led us to discover a treatment for a rare eye disease. Having brought this innovative therapy to eyecare, our research in this therapeutic area continues to expand
Our Contribution to Ophthalmology
Our research began in unveiling the potential of the nerve growth factor (NGF).Nerve growth factor (NGF) was discovered by the Italian neurobiologist, Professor Rita Levi-Montalcini, and her colleague biochemist, Dr. Stanley Cohen. In their research, Drs. Levi-Montalcini and Cohen uncovered that NGF plays a crucial role in the proliferation, differentiation and survival of sympathetic and sensory neurons (1).
In 2010 Dompé acquired the rights to research NGF-based treatments. Following several years of research, our committed team of scientists developed a recombinant protein of human nerve growth factor (rhNGF). It is produced using an innovative process that was developed to create a stable form of the NGF protein, by taking specific sequencing of NGF and forming the final molecule in prokaryotic cells.
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References
- The Nobel Prize in Physiology or Medicine 1986 (link to: https://www.nobelprize.org/prizes/medicine/1986/press-release/)