Drug repurposing screen to identify inhibitors of the RNA polymerase (nsp12) and helicase (nsp13) from SARS-CoV-2 replication and transcription complex
16/03/2024
Autori: Maria Kuzikov, Jeanette Reinshagen, Krzysztof Wycisk, Angela Corona, Francesca Esposito, Paolo Malune, Candida Manelfi, Daniela Iaconis, Andrea Beccari, Enzo Tramontano, Marcin Nowotny, Björn Windshügel, Philip Gribbon, Andrea Zaliani
Pubblicato in:
Virus ResearchProNGF processing in adult rat tissues and bioactivity of NGF prodomain peptides
01/03/2024
Autori: Marie Anne Makoudjou, Elena Fico, Pamela Rosso, Viviana Triaca, Lucio De Simone, Daniela Rossetti, Franca Cattani, Marcello Allegretti and Paola Tirassa
Pubblicato in:
FEBS Open Bio"DompeKeys": a set of novel substructure-based descriptros for efficient chemical space mapping, development and structural interpretation of machine learning models, and indexing of large databases
23/02/2024
Autori: Candida Manelfi, Valerio Tazzari, Filippo Lunghini, Carmen Cerchia, Anna Fava, Alessandro Pedretti, Pieter F. W. Stouten, Giulio Vistoli & Andrea Rosario Beccari
Pubblicato in:
Journal of CheminformaticsRole of airway epithelium in viral respiratory infections: Can carbocysteine prevent or mitigate them?
14/02/2024
Autori: Elisabetta Pace, Serena Di Vincenzo, Maria Ferraro, Luigi Lanata, Francesco Scaglione
Pubblicato in:
ImmunologyPhase IV multicenter, prospective, open-label clinical trial of cenegermin (rhNGF) for stage 1 neurotrophic keratopathy (DEFENDO)
13/02/2024
Autori: Pedram Hamrah, Mina Massaro-Giordano, David Schanzlin, Edward Holland, Gregg Berdy, Giovanni Goisis, Georgea Pasedis & Flavio Mantelli
Pubblicato in:
Ophthalmology and TherapyCombination Drug Therapy for the Management of Chronic Neuropathic Pain
16/12/2023
Autori: Serena Boccella, Lidia De Filippis, Cristina Giorgio, Laura Brandolini, Meghan Jones, Rubina Novelli, Ezio Amorizzo, Matteo Luigi Giuseppe Leoni, Gaetano Terranova, Sabatino Maione, Livio Luongo, Manuela Leone, Marcello Allegretti, Enrico Maria Minnella, Andrea Aramini
Pubblicato in:
Biomolecules Inhibition of C5aR1 as a promising approach to treat taxane-induced neuropathy
18/11/2023
Autori: C. Cristiano, C. Giorgio, P. Cocchiaro, S. Boccella, M.C. Cesta, V. Castelli, F.M. Liguori, M.R. Cuozzo, L. Brandolini, R. Russo, M. Allegretti
Pubblicato in:
CytokineStructure of human TRPM8 channel
19/10/2023
Autori: Sergii Palchevskyi, Mariusz Czarnocki-Cieciura, Giulio Vistoli, Silvia Gervasoni, Elżbieta Nowak, Andrea R. Beccari, Marcin Nowotny, Carmine Talarico
Pubblicato in:
Communications BiologyA non-intrusive data-driven reduced order model for parametrized CFD-DEM numerical simulations
15/10/2023
Autori: Arash Hajisharifi, Francesco Romanò, Michele Girfoglio, Andrea Beccari, Domenico Bonanni, Gianluigi Rozza
Pubblicato in:
Journal of Computational PhysicsEfficacy and Safety of Reparixin in Patients with Severe COVID-19 Pneumonia: A Phase 3, Randomized, Double-Blind Placebo-Controlled Study
05/10/2023
Autori: Lorenzo Piemonti, Giovanni Landoni, Antonio Voza, Massimo Puoti, Ivan Gentile, Nicola Coppola, Stefano Nava, Alessia Mattei, Franco Marinangeli, Giulia Marchetti, Paolo Bonfanti, Claudio Maria Mastroianni, Matteo Bassetti, Ernesto Crisafulli, Paolo Antonio Grossi, Alberto Zangrillo, Antonio Desai, Marco Merli, Maria Foggia, Marco Carpano, Lorenzo Schiavoni, Antonella D’Arminio Monforte, Luca Bisi, Gianluca Russo, Fabiana Busti, Cristina Rovelli, Elisabetta Perrotta, Giovanni Goisis, Elizabeth M. Gavioli, Sophie Toya, Maria De Pizzol, Flavio Mantelli, Marcello Allegretti, Enrico Maria Minnella
Pubblicato in:
Infectious Diseases and Therapy