Pipeline
Life sciences are radically improving the chances of treatment, even for diseases that have yet to find therapeutic answers. Thanks to new knowledge of biotechnology, ever-increasing computing power and the advancement of artificial intelligence, we will be able to respond to patients' needs even faster.
Clinical Pipeline
With our research and development pipeline, we target some of the highest-needing therapeutic areas.
Platform - Asset | Indication | |
---|---|---|
Ophtha - NGF | Front-of-the-eye: Neurotrophic Keratitis | |
Ophtha - NGF | Front-of-the-eye: Sjogren-related Dry Eye | |
Ophtha - NGF Intravitreal | Back-of-the-eye | |
NETosis - Reparixin | Community Acquired Pneumonia (CAP) | |
NETosis - Reparixin | Acute Respiratory Distress Syndrome (ARDS) | |
NETosis - Ladarixin | Type 1 Diabetes – Early Onset | |
NETosis - Ladarixin | Type 1 Diabetes – Insulin resistant | |
Primary Care - KLS-Gaba | Low-back pain |
Ophtha - NGF
Indication: Front-of-the-eye: Neurotrophic Keratitis
Project Status:
Ophtha - NGF
Indication: Front-of-the-eye: Sjogren-related Dry Eye
Project Status:
Ophtha - NGF Intravitreal
Indication: Back-of-the-eye
Project Status:
NETosis - Reparixin
Indication: Community Acquired Pneumonia (CAP)
Project Status:
NETosis - Reparixin
Indication: Acute Respiratory Distress Syndrome (ARDS)
Project Status:
NETosis - Ladarixin
Indication: Type 1 Diabetes – Early Onset
Project Status:
NETosis - Ladarixin
Indication: Type 1 Diabetes – Insulin resistant
Project Status:
Primary Care - KLS-Gaba
Indication: Low-back pain
Project Status:
Latest Publications
Drug repurposing screen to identify inhibitors of the RNA polymerase (nsp12) and helicase (nsp13) from SARS-CoV-2 replication and transcription complex
16/03/2024
Authors: Maria Kuzikov, Jeanette Reinshagen, Krzysztof Wycisk, Angela Corona, Francesca Esposito, Paolo Malune, Candida Manelfi, Daniela Iaconis, Andrea Beccari, Enzo Tramontano, Marcin Nowotny, Björn Windshügel, Philip Gribbon, Andrea Zaliani
Published in:
Virus ResearchProNGF processing in adult rat tissues and bioactivity of NGF prodomain peptides
01/03/2024
Authors: Marie Anne Makoudjou, Elena Fico, Pamela Rosso, Viviana Triaca, Lucio De Simone, Daniela Rossetti, Franca Cattani, Marcello Allegretti and Paola Tirassa
Published in:
FEBS Open Bio"DompeKeys": a set of novel substructure-based descriptros for efficient chemical space mapping, development and structural interpretation of machine learning models, and indexing of large databases
23/02/2024
Authors: Candida Manelfi, Valerio Tazzari, Filippo Lunghini, Carmen Cerchia, Anna Fava, Alessandro Pedretti, Pieter F. W. Stouten, Giulio Vistoli & Andrea Rosario Beccari
Published in:
Journal of Cheminformatics